diff --git a/core-modules/000QubesVm.py b/core-modules/000QubesVm.py
index f72b51b2..fc15dde6 100644
--- a/core-modules/000QubesVm.py
+++ b/core-modules/000QubesVm.py
@@ -566,6 +566,10 @@ class QubesVm(object):
             return False
         if len(name) > 31:
             return False
+        if name == 'lost+found':
+            # avoid conflict when /var/lib/qubes/appvms is mounted on
+            # separate partition
+            return False
         return re.match(r"^[a-zA-Z][a-zA-Z0-9_.-]*$", name) is not None
 
     def pre_rename(self, new_name):