Only the Debian package had declared the dependecy. And apparently, fedora-26-minimal does not include the iptables package by default anymore.
@@ -228,6 +228,7 @@ Scripts required to handle dom0 updates.
%package networking
Summary: Networking support for Qubes VM
Requires: ethtool
+Requires: iptables
Requires: net-tools
Requires: nftables
Requires: socat